Ferric hydroxamate uptake system contributes to Edwardsiella ictaluri virulence
نویسندگان
چکیده
منابع مشابه
The Role of Edwardsiella ictaluri TonB Mutant in Edwardsiella ictaluri Virulence
Edwardsiella ictaluri is a Gram-negative facultative intracellular pathogen that causes enteric septicemia in catfish (ESC). Stress factors including poor water quality, poor diet, rough handling, overcrowding, and water temperature fluctuations increase fish susceptibility to ESC. The TonB energy transducing system (TonB-ExbB-ExbD) and TonB-dependent transporters of Gram-negative bacteria supp...
متن کاملThe Role of TonB Gene in Edwardsiella ictaluri Virulence
Edwardsiella ictaluri is a Gram-negative facultative intracellular pathogen that causes enteric septicemia in catfish (ESC). Stress factors including poor water quality, poor diet, rough handling, overcrowding, and water temperature fluctuations increase fish susceptibility to ESC. The TonB energy transducing system (TonB-ExbB-ExbD) and TonB-dependent transporters of Gram-negative bacteria supp...
متن کاملDomain analysis of the Edwardsiella tarda ferric uptake regulator.
Recent studies have shown that the ferric uptake regulator (Fur) of Edwardsiella tarda (Fur(Et)) shares high sequence identity with the Escherichia coli Fur (Fur(Ec)) at the N-terminal DNA-binding region. In the present study, the functional importance of the C-terminal region of Fur(Et) was investigated. It was found that Fur(Et) bearing deletion of the C-terminal 12 residues still possesses m...
متن کاملStress-related genes promote Edwardsiella ictaluri pathogenesis
Edwardsiella ictaluri is a Gram-negative facultative anaerobic rod and the causative agent of enteric septicemia of channel catfish (ESC), which is one of the most prevalent diseases of catfish, causing significant economic losses in the catfish industry. E. ictaluri is resistant to complement system and macrophage killing, which results in rapid systemic septicemia. However, mechanisms of E. i...
متن کاملAlbomycin uptake via a ferric hydroxamate transport system of Streptococcus pneumoniae R6.
The antibiotic albomycin is highly effective against Streptococcus pneumoniae, with an MIC of 10 ng/ml. The reason for the high efficacy was studied by measuring the uptake of albomycin into S. pneumoniae. Albomycin was transported via the system that transports the ferric hydroxamates ferrichrome and ferrioxamine B. These two ferric hydroxamates antagonized the growth inhibition by albomycin a...
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ژورنال
عنوان ژورنال: Microbial Pathogenesis
سال: 2016
ISSN: 0882-4010
DOI: 10.1016/j.micpath.2016.09.018